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SEMAX · 10 MG | Enfoque, Memoria y Rendimiento Cognitivo

Product Details

  • Technical Name: Semax 10 mg, Polvo Liofilizado para Investigación
  • Laboratory / Brand: Syntex Labs
  • Active Ingredient (INN): Semax - Heptapéptido sintético análogo de la ACTH (4-7)
  • Pharmaceutical Form: Polvo Liofilizado para Solución Inyectable
  • Concentration: 10 mg/vial
  • CAS Number: 80714-61-0
  • Internal SKU: SKU-SEMAX-10MG-80714610
Syntex Labs Semax - Heptapéptido sintético análogo de la ACTH (4-7) Polvo Liofilizado para Solución Inyectable CAS: 80714-61-0
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Product · peptidos

SEMAX · 10 MG | Enfoque, Memoria y Rendimiento Cognitivo

Upgraded Formula Best Seller Longevity & Performance

30 Servings Per Container: US$3.33 / serving

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US$99.99 USD
In stock (10,000 piece)
Semax is a synthetic heptapeptide neuropeptide analog of the C-terminal fragment of ACTH that increases BDNF and NGF, activates neurotransmitter systems, and protects neurons. Ideal for research on focus, memory, and neuroprotection. Lab grade with purity ≥99% by HPLC-MS. Each vial contains 10 mg of Semax as sterile lyophilized powder, designed for in vitro and animal model scientific research. Manufactured under strict GMP standards, with complete batch traceability and Certificate of Analysis available. SKU: SKU-SEMAX-10MG. CAS: 80714-61-0. Store at 2-8°C in a dry place protected from light.

Semax is a synthetic heptapeptide neuropeptide designed to improve attention, memory, and concentration capacity. It was developed at the Institute of Molecular Genetics of the Russian Academy of Sciences and has been extensively studied for its nootropic, neuroprotective, and anxiolytic properties. Semax sharpens mental clarity, maintains focus over long periods, and maximizes intellectual performance, making it ideal for athletes, professionals, and anyone needing optimal cognitive performance under pressure. Unlike traditional stimulants such as caffeine or psychostimulants, Semax acts through neurotrophic and neuromodulatory mechanisms, improving brain function without significant side effects such as anxiety, tachycardia, or insomnia.

Primary Benefit: Focus and Memory

At its core, Semax is designed to improve attention, memory, and concentration capacity through regulation of neurotrophins and neurotransmitter systems. Semax increases levels of Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF), proteins crucial for neuronal survival, growth, and plasticity, resulting in improved learning and memory . It also activates dopaminergic and serotonergic systems in the brain, positively influencing mood, motivation, and cognitive functions . Its intranasal or injectable administration allows the peptide to efficiently cross the blood-brain barrier, providing rapid effects on focus and mental clarity .

Secondary Benefits: Neuroprotection, Mental Recovery, and Cognitive Resilience

Semax's action on the central nervous system triggers a cascade of biological effects impacting multiple aspects of mental performance:

Improved Focus and Concentration: Semax increases the ability to maintain attention on complex and lengthy tasks, sharpening mental clarity and eliminating "brain fog." Studies have demonstrated that Semax improves cognitive function in patients with stroke and cognitive impairment .

Improved Memory and Learning Speed: Semax improves memory consolidation and learning speed, facilitating information retention and acquisition of new skills. Animal model studies have demonstrated that Semax increases sensory attention and facilitates learning capacity .

Neuroprotection and Inflammation Reduction: Semax protects neurons from damage, reduces inflammation, and promotes neurogenesis, making it a promising agent for prevention and treatment of central nervous system pathologies . Studies have demonstrated that Semax reduces brain damage in ischemia and stroke models .

Reduction of Mental Fatigue: Semax reduces mental fatigue after intense training or work sessions, improving cognitive recovery and maintaining mental performance during prolonged periods of high demand.

Mood and Motivation Regulation: Semax activates dopaminergic and serotonergic systems, positively influencing mood, motivation, and cognitive functions .

Pairing Strategy: Semax + Selank

Semax and Selank constitute a synergistic stack for enhancing mental performance and neuroprotection. Both peptides were developed at the same Russian institute and share complementary mechanisms. While Semax improves focus, memory, and neuroplasticity through BDNF and NGF increase, Selank provides calm focus through GABAergic system modulation and enkephalin degradation inhibition. The combination of both offers a comprehensive approach to cognitive performance, stress resilience, and neuroprotection.
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SEMAX · 10 MG | Enfoque, Memoria y Rendimiento Cognitivo

Semax: El Neuropéptido para el Enfoque Nítido y el Rendimiento Cognitivo Máximo

Para el atleta que busca mantener la concentración durante la competición, el profesional que enfrenta tareas de alta exigencia y cualquier persona que necesite un rendimiento cognitivo óptimo, Semax representa una revolución en la optimización cerebral. Este neuropéptido sintético, desarrollado en el Instituto de Genética Molecular de la Academia de Ciencias de Rusia, agudiza la claridad mental, mantiene el enfoque durante largos períodos y maximiza el rendimiento intelectual.

Beneficio Principal: Enfoque y Memoria

Semax mejora la atención, la memoria y la capacidad de concentración a través de la regulación de neurotrofinas y sistemas de neurotransmisores. Los estudios han demostrado que Semax:

Aumenta los niveles de BDNF y NGF, proteínas cruciales para la plasticidad neuronal y la supervivencia celular .

Activa los sistemas dopaminérgico y serotoninérgico, mejorando el estado de ánimo, la motivación y las funciones cognitivas .

Protege las neuronas del daño y reduce la inflamación, promoviendo la neurogénesis .

Cruza eficientemente la barrera hematoencefálica, proporcionando efectos rápidos en el enfoque y la claridad mental .

Evidencia Científica de Eficacia

La eficacia de Semax está respaldada por décadas de investigación en modelos animales y estudios clínicos en humanos. Los estudios han demostrado que Semax:

Mejora la función cognitiva en pacientes con accidente cerebrovascular y deterioro cognitivo .

Aumenta la atención sensorial y facilita la capacidad de aprendizaje en modelos animales .

Reduce el daño cerebral en modelos de isquemia y accidente cerebrovascular .

No afecta los niveles de cortisol, evitando la respuesta hormonal al estrés .

Impacto en el Rendimiento Cognitivo y la Recuperación

Semax es una herramienta invaluable para:

Atletas de alto rendimiento: Mejorando el enfoque y la concentración durante la competición y el entrenamiento, y reduciendo la fatiga mental .

Profesionales de alta exigencia: Proporcionando mayor claridad mental y capacidad de concentración para tareas complejas y de alta presión.

Estudiantes: Mejorando la memoria, la velocidad de aprendizaje y la capacidad de retención de información.

Optimizadores: Optimiza el rendimiento cognitivo para un funcionamiento mental máximo.

Key Benefits of Semax Increased Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF) Semax increases BDNF and NGF levels, proteins crucial for neuronal survival, growth, and plasticity . BDNF is fundamental for synaptic plasticity, learning, and memory, while NGF is essential for survival and maintenance of cholinergic neurons . Studies have demonstrated that Semax increases BDNF expression in the hippocampus and prefrontal cortex, resulting in improved learning and memory . This effect is comparable to antidepressants and other nootropic agents that act through neurotrophin regulation . Neurotransmitter Modulation (Dopamine, Serotonin, and Acetylcholine) Semax activates dopaminergic and serotonergic systems in the brain, positively influencing mood, motivation, and cognitive functions . Dopamine is fundamental for attention, motivation, and reward-based learning, while serotonin regulates mood, anxiety, and cognitive function . Semax also modulates the cholinergic system, which is essential for attention and memory . This neuromodulatory effect is responsible for Semax's nootropic effects, improving focus, mental clarity, and cognitive performance without the side effects of traditional stimulants . Neuroprotection and Inflammation Reduction Semax protects neurons from damage, reduces inflammation, and promotes neurogenesis . Studies in cerebral ischemia models have demonstrated that Semax reduces cerebral infarct size and improves neurological recovery . Semax also reduces pro-inflammatory cytokine production and oxidative stress, protecting the brain from damage and aging . This neuroprotective effect is especially relevant for athletes and professionals facing intense cognitive and physical stress. Improved Focus, Concentration, and Mental Clarity Semax increases the ability to maintain attention on complex and lengthy tasks, sharpening mental clarity and eliminating "brain fog." Studies have demonstrated that Semax improves cognitive function in patients with stroke and cognitive impairment . In animal models, Semax has demonstrated increased sensory attention by 2-3 fold and facilitated learning capacity by 1.5 fold . This effect is especially valuable for athletes needing to maintain focus during competition and training. Improved Memory and Learning Speed Semax improves memory consolidation and learning speed, facilitating information retention and acquisition of new skills . Studies have demonstrated that Semax improves working memory and spatial memory in animal models . This effect is mediated by BDNF increase and synaptic plasticity in the hippocampus . Reduction of Mental Fatigue and Improved Cognitive Recovery Semax reduces mental fatigue after intense training or work sessions, improving cognitive recovery and maintaining mental performance during prolonged periods of high demand. Studies have demonstrated that Semax reduces mental fatigue and improves cognitive performance in patients with chronic fatigue syndrome . Mood and Motivation Regulation Semax activates dopaminergic and serotonergic systems, positively influencing mood, motivation, and cognitive functions . This effect is especially valuable for athletes facing stress and anxiety during competition, improving mental resilience and performance under pressure.
Function and Mechanism of Action of Semax Semax (Met-Glu-His-Phe-Pro-Gly-Pro) is a synthetic heptapeptide developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It is an analog of the C-terminal fragment of adrenocorticotropic hormone (ACTH 4-10: Met-Glu-His-Phe-Arg-Trp-Gly) but with amino acid substitutions that confer greater metabolic stability and a prolonged half-life . Semax acts through multiple neurochemical and neurotrophic mechanisms to improve cognitive function and protect the central nervous system. Detailed Mechanism of Action: Neurotrophin Increase (BDNF and NGF): Semax increases BDNF and NGF expression in the hippocampus and prefrontal cortex . BDNF is fundamental for synaptic plasticity, learning, and memory, while NGF is essential for survival and maintenance of cholinergic neurons . Semax activates the TrkB signaling pathway, which is the BDNF receptor, promoting synaptic plasticity and neurogenesis . Neurotransmitter Modulation: Semax activates dopaminergic, serotonergic, and cholinergic systems in the brain . Dopamine is fundamental for attention, motivation, and reward-based learning, while serotonin regulates mood, anxiety, and cognitive function . The cholinergic system is essential for attention and memory . Semax increases dopamine and serotonin release in the striatum and prefrontal cortex , and modulates acetylcholinesterase activity . Neuroprotection: Semax protects neurons from damage, reduces inflammation, and promotes neurogenesis . Studies in cerebral ischemia models have demonstrated that Semax reduces cerebral infarct size and improves neurological recovery . Semax reduces pro-inflammatory cytokine (TNF-α, IL-1β) production and oxidative stress, protecting the brain from damage and aging . Semax also activates the PI3K/Akt signaling pathway, which promotes cell survival and neuroprotection . Synaptic Plasticity Modulation: Semax promotes synaptic plasticity through BDNF increase and TrkB pathway activation . This effect is fundamental for learning and memory, and is comparable to antidepressants and other nootropic agents that act through neurotrophin regulation
How to Use Semax Route of Administration: Injectable via subcutaneous (SC) or intramuscular (IM). Subcutaneous administration is the most common and preferred, as it allows gradual and constant absorption. Injection sites should be rotated (abdomen, thigh, gluteal region). Semax is also commonly administered as a nasal spray in Russian clinical practice . Reconstitution: The product is presented as a lyophilized powder in a sterile vial. It must be reconstituted with bacteriostatic water for injection (or sterile water for injection) before use. Add the diluent slowly, gently swirling the vial to dissolve the powder. Do not shake vigorously. Research Protocol: Dosage and frequency must be determined by the researcher according to protocol goals. Common research protocols for Semax use: Dose: 0.5-2 mg per administration (injectable) or 0.1% nasal solution (2-3 drops 3-4 times daily) . Frequency: 1-2 times daily (injectable) or as needed (nasal spray). Duration: Cycles of 10-20 days, repeated as needed . Research cycles of 2 to 4 weeks are recommended to assess changes in focus, memory, and cognitive function . Storage: The lyophilized powder should be stored in a cool, dry place, protected from light and at controlled temperature (2-8°C). Once reconstituted, it must be refrigerated (2-8°C) and used within 30 days . Important Notice: Product intended EXCLUSIVELY FOR SCIENTIFIC RESEARCH in vitro and in animal models. Not approved for human use by FDA . Semax is approved only in Russia and other CIS countries for ischemic stroke and cognitive impairment . The dosages and protocols mentioned are examples for research and do not constitute medical advice. The researcher is solely responsible for safety and compliance with applicable regulations during the development of the research protocol.
Ingredients of Semax Active Ingredient: Semax (Heptapeptide Met-Glu-His-Phe-Pro-Gly-Pro): A synthetic neuropeptide analog of the C-terminal fragment of ACTH that acts as a modulator of neurotrophins (BDNF and NGF), activator of neurotransmitter systems (dopaminergic, serotonergic, and cholinergic), and neuroprotective agent . It is composed of 7 amino acids: Methionine (Met), Glutamic Acid (Glu), Histidine (His), Phenylalanine (Phe), Proline (Pro), Glycine (Gly), and Proline (Pro). The active ingredient purity is ≥99% by HPLC-MS. Excipients: Mannitol: A sugar alcohol that acts as a cryoprotectant and bulking agent, used to stabilize the peptide structure during the lyophilization process. Water for Injection (WfI): High-purity water (USP/EP grade) used as a vehicle in the lyophilization process. Note for Researchers: This product is a high-purity synthetic peptide (>99% by HPLC-MS), manufactured without unnecessary additives, preservatives, or fillers. Its production is carried out under strict quality control standards (GMP). Semax is not FDA-approved for human use and is intended exclusively for in vitro and animal model scientific research.
Onset Time & Expected Results of Semax Onset of Action (Minutes to Hours): Semax begins acting within the first hours after administration, with effects on focus and mental clarity observed within the first days . Intranasal administration allows the peptide to efficiently cross the blood-brain barrier, providing rapid effects on focus and mental clarity . Measurable Benefits (1-2 Weeks): Improved focus, concentration, and mental clarity are typically the first observable effects. Studies have demonstrated that Semax improves cognitive function in patients with stroke and cognitive impairment within the first weeks of treatment . Improved memory and learning speed are also observable in this period . Full Effect (4-12 Weeks): For significant changes in neuroplasticity, neuroprotection, and long-term cognitive function, the full effect often requires 4-12 weeks of consistent use according to the research protocol . Studies have demonstrated that Semax's effects on BDNF and synaptic plasticity accumulate over time . Factors Influencing Results: The speed and magnitude of results depend on dose administered, administration frequency, subject's nutritional status, age, and adherence to the research protocol.
Clinical Research & 3rd Party Test Results of Semax Scientific evidence on Semax is supported by decades of research in animal models and human clinical studies, developed primarily in Russia, where the peptide is approved for ischemic stroke and cognitive impairment . Research has demonstrated its nootropic, neuroprotective, and anxiolytic effects. Clinical Evidence in Humans: Studies in Ischemic Stroke: Semax is used in Russian clinical practice for ischemic stroke, where it has been demonstrated to reduce cerebral infarct size and improve neurological recovery . Studies have demonstrated that Semax improves cognitive function and reduces disability in stroke patients . Studies in Cognitive Impairment: Semax has demonstrated improved cognitive function in patients with cognitive impairment of various etiologies, including cerebrovascular disease and aging . Studies have demonstrated that Semax improves attention, memory, and processing speed . Studies in Chronic Fatigue Syndrome: Semax has demonstrated reduced mental fatigue and improved cognitive performance in patients with chronic fatigue syndrome . Evidence in Animal Models: Effects on Attention and Learning: Semax has demonstrated increased sensory attention by 2-3 fold and facilitated learning capacity by 1.5 fold in animal models . Effects on Neuroprotection: Semax has demonstrated reduced cerebral infarct size in ischemia models and improved neurological recovery . Effects on BDNF: Semax has demonstrated increased BDNF expression in the hippocampus and prefrontal cortex in animal models . Regulatory Status: Approval in Russia and other CIS Countries: Semax is approved in Russia and other CIS countries for ischemic stroke and cognitive impairment . FDA Classification: Semax is classified as Category 2 by FDA (substance under evaluation) and is not approved for any use in the United States . Research Use: Semax is available for in vitro and animal model scientific research. Products sold through online vendors without a prescription are not regulated by FDA . Syntex Labs Quality Standards: Lab Grade: Purity ≥99% by HPLC-MS. QR Tracking: Complete batch traceability. Secure Batch Label: "Scratch to See" security system. 3rd Party Results: Access to Certificates of Analysis (COA) from accredited external laboratories.

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